Lois Smith, MD, PhD
Professor of Ophthalmology, Harvard Medical School
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Major Scientific Accomplishment
The Children’s Hospital Intellectual and Developmental Disabilities Research Center (IDDRC) is one of the oldest centers of its kind in the United States. The Center is led by Scott Pomeroy, M.D., Ph.D., Neurologist in Chief and IDDRC Director; and Associate Directors Clifford Woolf, M.D., Ph.D., Director of the F.M. Kirby Neurobiology Program at CHB; and Louis Kunkel, Ph.D., Director of the CHB Genomics Program. Sixty-six Center investigators representing fifteen Departments and Divisions from five adjacent institutions (Harvard Medical School, Children’s Hospital, the Brigham and Women’s Hospital, the Beth Israel Deaconess Medical Center and the Dana Farber Cancer Institute) carry out research that falls into two major areas: Genetics and Neuroscience. Within the area of neuroscience, Center research falls into two major programmatic categories: Basic Neuroscience, and Clinical/Translational Neuroscience.
Our research is in keeping with the mission of the program and all projects satisfy at least one of the targeted areas of relevance defined by the NIH for a national network of Intellectual and Developmental Disabilities Research Centers (IDDRCs). This center network represents the nation’s first and foremost sustained effort to prevent and treat disabilities through biomedical and behavioral research. IDDRCs also contribute to the development and implementation of evidence-based practices by evaluating the effectiveness of biological, biochemical, and behavioral interventions; developing assistive technologies; and advancing prenatal diagnosis and newborn screening.The IDDRC network currently includes 21 member organizations of the Association of University Centers on Disabilities, 14 Centers with P30 core grant funding from the Eunice Kennedy Shriver National Institute for Child Health and Human Development (NICHD) and 7 Centers that use alternative funding mechanisms within the National Institutes of Health (NIH) to support projects relevant to intellectual disabilities.
To support our ongoing funding, IDDRC members are expected to cite our Center (“BCH IDDRC, P30 HD18655”) in all publications that result from work supported by one or more of our Core facilities.